Are probiotics a possible treatment of periodontitis? Probiotics against periodontal disease: a systematic review.

Introduction Periodontal disease is one of the most prevalent oral diseases. Until now, periodontal disease treatments offer good results but periodontal pockets can be immediately recolonised by pathogenic bacteria. The limitations of these treatments have led to the need to find more effective alternatives that reinforce the periodontal treatments.Aim To evaluate the clinical effect of probiotics as an adjuvant treatment to scaling and root planing in patients with periodontitis.Materials and methods An electronic search in Medline (via PubMed) of randomised clinical trials published in the last ten years that include the effects of using probiotics in periodontal disease was performed.Results In total, ten trials were included and in seven of them the evaluated clinical parameters were significantly improved in the test group compared to the placebo group. In five trials, a significant reduction of the main periodontal pathogens was reported. No side effects were observed in any trial.Conclusions The administration of probiotics as an adjuvant treatment to periodontal treatment helps improve the clinical parameters, significantly decreases the concentration of the main periodontal pathogens and does not cause any side effects.

Perioral Aerosol Sequestration Suction Device Effectively Reduces Biological Cross-Contamination in Dental Procedures.

OBJECTIVE: The infection risk during dental procedures is a common concern for dental professionals which has increased due to coronavirus (severe acute respiratory syndrome coronavirus 2) pandemic. The development of devices to specifically mitigate cross-contamination by droplet/splatter is crucial to stop infection transmission. The objective of this study is to assess the effectiveness of a perioral suction device (Oral BioFilter, OBF) to reduce biological contamination spread during dental procedures. MATERIALS AND METHODS: Forty patients were randomized 1:1 to a standard professional dental hygiene treatment with OBF and without. Adenosine triphosphate (ATP) bioluminescence assay was used to evaluate the spread of potential contaminants. The total number of relative light units (RLU) from key dental operatory locations: operator's face-shield, back of the surgical operator's-gloves, patient's safety-goggles, and instrumental table were measured. Percentage contamination reductions between control and OBF were compared. STATISTICAL ANALYSIS: Primary outcome, total RLU, was analyzed by comparing the means of logged data, using a two-sided two-sample t-test. Secondary outcomes as RLU of logged data for the different locations were analyzed in the same way. Proportion of patients from whom different locations reported events (clean, acceptable, and failure) were analyzed by using Fisher's exact test. RESULTS: For the whole dental environment, RLUs reduction (<150 units) achieved with OBF was 98.4% (97.4-99%). By dental operatory location the reduction in RLUs was from 99.6%, on the operator face-shield, to 83% on instrumental table. The control group reported a very high percentage of failures, (>300) being 100% on the surfaces closer to the patient's mouth and decreasing to 70% on instrumental table. In contrast, the higher failure percentage in the OBF group was found on the patient's goggles (40%), while the operator face-shield showed an absence of contamination. CONCLUSION: OBF device has shown efficient reduction of biological aerosol cross-contamination during dental procedures as proved by ATP-bioluminescence assay. Nevertheless, for maximum safety, its use must be combined with standard protective gear such as goggles, face shield, and surgical gloves.

Disbiosis como factor determinante de enfermedad oral y sistémica: importancia del microbioma / Dysbiosis as a determinant factor of systemic and oral pathology: importance of microbiome

Los avances en los estudios de genética y epigenética modifican algunos conceptos de salud y enfermedad que se habían mantenido intactos durante décadas. En este sentido, en los últimos años se está otorgando un protagonismo creciente a microorganismos que han acompañado durante millones de años de evolución a los seres vivos superiores. Los genes de estos y de su microbiota constituyen un microbioma que interviene en el mantenimiento de la salud. La boca es lugar de asiento de gran variedad de microorganismos, cuyo control ayuda a estabilizar la enfermedad oral y sistémica. El objetivo del presente artículo es actualizar algunos conceptos relativos al microbioma oral y de su vinculación con la salud oral y general (AU)

Advances in genetic and epigenetic studies modified some concepts of health and disease that had been kept intact for decades. In this respect, in the last few years, microorganisms that have evolved with superior life forms for millions of years have taken an increased prominence. The genes of organisms and their microbiota constitute a microbiome that intervenes in health maintenance. The oral cavity is inhabited by a variety of microorganisms, their control aids in stabilising oral and systemic disease. The objective of this article is to update some concepts related to oral microbiome and its correlation with general and oral health (AU)

Dysbiosis as a determinant factor of systemic and oral pathology: importance of microbiome. / Disbiosis como factor determinante de enfermedad oral y sistémica: importancia del microbioma.

Advances in genetic and epigenetic studies modified some concepts of health and disease that had been kept intact for decades. In this respect, in the last few years, microorganisms that have evolved with superior life forms for millions of years have taken an increased prominence. The genes of organisms and their microbiota constitute a microbiome that intervenes in health maintenance. The oral cavity is inhabited by a variety of microorganisms, their control aids in stabilising oral and systemic disease. The objective of this article is to update some concepts related to oral microbiome and its correlation with general and oral health.